Shikonin- into entsha yemvelo elwa namagciwane eyenza uguquko lwama-antibiotic
Muva nje, ososayensi bathole into entsha yemvelo ye-antibacterial, i-shikonin, engcebweni yombuso wezitshalo. Lokhu okutholakele kuye kwavusa ukunaka nesasasa emhlabeni wonke. I-Shikonin inomsebenzi we-antibacterial we-spectrum ebanzi futhi kulindeleke ukuthi ibe yikhandidethi ebalulekile ekuthuthukisweni kwama-antibiotic amasha. I-Shikonin ikhishwa esitshalweni esibizwa ngokuthi i-comfrey, esimila ezingxenyeni zase-Asia, eYurophu naseNyakatho Melika. I-Shikonin inombala onsomi ogqamile futhi isetshenziswa kakhulu kumadayi nasemithini yemithi. Kodwa-ke, ucwaningo lwakamuva lubonisa ukuthi i-shikonin ayinhle nje kuphela, kodwa futhi i-ejenti engase ibe ne-antibacterial.
Ekuhlolweni, ososayensi bathola ukuthi i-shikonin inomphumela oqinile wokuvimbela ezinhlobonhlobo zamagciwane kanye nesikhunta. Akukhona lokho kuphela, kungase futhi kube nomthelela wokubulala amagciwane kwamanye amagciwane amelana nemithi, okubaluleke kakhulu enkingeni enzima yamanje yokumelana nama-antibiotic. Abacwaningi baphinde bathola ukuthi i-shikonin ingakwazi ukusebenzisa umphumela wayo wokulwa namagciwane ngokubhubhisa ulwelwesi lwamangqamuzana e-bacterial futhi luvimbele ukukhula kwalo. Le nqubo ihlukile emithi elwa namagciwane ekhona, enikeza isiqondiso esisha sokuthuthukiswa kwama-antibiotic. Ukuze kuqhutshekwe nokuqinisekisa ukusebenza kahle nokuphepha kwe-shikonin, abacwaningi benze uchungechunge lwe-in vivo kanye nokuhlolwa kwe-in vitro.
Into ejabulisayo ukuthi i-shikonin ibonise umsebenzi omuhle wezinto eziphilayo ngaphandle kokubangela imiphumela emibi kakhulu. Lokhu kwenza i-shikonin ibe i-ejenti elwa namagciwane engaba khona futhi ifaka ubungqabavu obusha ocwaningweni nasekuthuthukisweni kwemithi elwa namagciwane. Nakuba ukutholakala kwe-shikonin kuye kwaletha ithemba, ososayensi baphinde bakhumbuze abantu ukuthi ukuthuthukiswa nokusetshenziswa kwemithi elwa namagciwane kudingeka kuqaphe. Ukusetshenziswa kabi nokusetshenziswa ngokweqile kwama-antimicrobial kuye kwaholela enkingeni yomhlaba wonke yokungazweli emishanguzweni, ngakho-ke ama-antibiotic amasha kufanele asetshenziswe futhi alawulwe ngokunengqondo.
Ngaphezu kwalokho, ososayensi baphinde bacela abatshalizimali kanye nohulumeni ukuthi banyuse imali kanye nokwesekwa kocwaningo nokuthuthukiswa kwemithi elwa namagciwane ukuze kuthuthukiswe ukwakhiwa kwemishanguzo emisha elwa namagciwane. Njengamanje, ucwaningo nge-shikonin seludonse ukunaka emhlabeni wonke. Inqwaba yezinkampani ezenza imithi nezikhungo zocwaningo zengeza ucwaningo nokuthuthukiswa kwama-antibacterial ahlobene ne-shikonin.
Abacwaningi bathi bazoqhubeka nokutadisha isakhiwo samangqamuzana nendlela yokusebenza ye-shikonin ukuze bahlole kangcono amandla ayo. Ngokuqhubeka okuqhubekayo emkhakheni wemithi elwa namagciwane, ukutholakala kwe-shikonin kuye kwafaka umfutho omusha ekuguqukeni kwama-antibiotic. Inikeza ithemba futhi ibeka isisekelo sesizukulwane esisha semithi elwa namagciwane. Singabona kusengaphambili ukuthi ucwaningo nge-shikonin luzokhuthaza ukuqanjwa kabusha emkhakheni wezokwelapha futhi silethe ukukhetha kanye namathemba amaningi empilweni yomuntu.
Isikhathi sokuthumela: Jul-27-2023
