Withanolides

Umkhuba wokuthuthuka weWithanolides, eyaziwa nangokuthi i-20-Hydroxyecdysone (20-Hydroxyecdysone), ihomoni ye-phytosteroid etholakala kabanzi ezitshalweni eziningi zemvelo, njenge-withan (ebizwa ngokuthi i-húanbān noma i-hūnabǎn) ne-Asiatic saxifrage (eyaziwa ngokuthi Uma, Cynomorium songaricum). I-Withanolides isetshenziswe kabanzi emikhakheni yemikhiqizo yokunakekelwa kwezempilo nemithi, futhi idonse ukunaka okuningi ngezinzuzo zayo eziningi nezinkambu ezingase zisetshenziswe.

Okulandelayo yinkambiso yentuthuko yama-analides: Ucwaningo lwesayensi nentuthuko: Ziyanda izikhungo zocwaningo nezinkampani zinentshisekelo ocwaningweni lwama-analides. Ososayensi benza ucwaningo olujulile mayelana nokwakheka kwamakhemikhali, umsebenzi webhayoloji kanye nemiphumela ye-analides emzimbeni womuntu ukuze baveze izindawo ezingase zisetshenziswe kanye nezindlela.

Ukusungulwa nokuthuthukiswa komkhiqizo: Njengoba ucwaningo olumayelana nama-analides luqhubeka nokujula, kulindeleke ukuthi kungene emakethe imikhiqizo emisha ehambisana ne-analide. Le mikhiqizo ingase isebenzise izindlela ezihlukene zokukhipha kanye nokwakheka ukuze kuhlinzekwe ngekhwalithi ephezulu futhi enamandla kakhulu ngemikhiqizo ene-analides.

Ukukhula Kwesidingo Semakethe: Ukwenyuka kokukhathazeka ngempilo nokuphila kahle kuholele ekukhuleni kwesidingo sezinhlanganisela zezitshalo zemvelo. Njengesithako esisebenzayo semvelo, i-ananalides ithole ukunakwa okubanzi nomusa ekunakekelweni kwezempilo kanye nemakethe yokondleka kwezemidlalo.2. Imininingwane yomkhiqizo ye-analides Izinga lomkhiqizo nomthelela we-analides kungahluka kuye ngomkhiqizi kanye nendlela yokulungisa umkhiqizo.

Okulandelayo ulwazi olujwayelekile mayelana nemikhiqizo ye-analides: Indlela yokukhipha: i-anolide ivamise ukukhishwa ku-nightshade. Inqubo yokukhipha idinga ukunakwa kwendlela yokugcina ubumsulwa bayo kanye nezithako ezisebenzayo. Izindlela ezivamile zokukhipha zihlanganisa ukukhishwa kwe-solvent kanye nokuhlanzwa ukuze kuqinisekiswe ukuhlanzeka okuphezulu nama-analides.

Ifomu lezentengiselwano: imikhiqizo ene-analides ivamise ukuthengiswa ngendlela yamaphilisi, amaphilisi, impushana noma uketshezi. Amafomu ahlukene angakwazi ukuzivumelanisa kangcono nezidingo kanye nemikhuba yokusebenzisa yabasebenzisi. Okuqukethwe kwesithako esisebenzayo: okuqukethwe kwama-analides kungahluka kumkhiqizo kuye ngomkhiqizo, kuye ngokulungiswa, ukugxila kanye nokulawulwa kwekhwalithi yemikhiqizo ehlukene. Ngokuvamile, okuqukethwe kwama-analides kufanele kuboniswe ngokucacile kulebula yomkhiqizo.

Iziphakamiso zokusetshenziswa: Indlela yokusebenzisa, umthamo, kanye nemvamisa yokusetshenziswa kwama-analides kungahluka ngokuya ngezinkomba zomkhiqizo. Abasebenzisi kufanele bafunde ilebula yomkhiqizo ngokucophelela futhi bayisebenzise ngokulandela imiyalelo.

Inkambu yesicelo ye-ananalides ene-analides inezinhlelo zokusebenza ezingase zisetshenziswe ezihlukahlukene, okulandelayo ezinye zezinto ezibalulekile: Umsoco wezemidlalo kanye nokukhula kwemisipha okuthuthukisiwe: i-ananalides isetshenziswa kabanzi ekudleni kwezemidlalo ukuthuthukisa ukusebenza kwezemidlalo, ukukhuthaza ukukhula kwemisipha, ukwandisa amandla emisipha nokubekezela. . I-ananalides kukholakala ukuthi yandisa ukwakheka kwamaprotheni futhi ibe nomthelela ezindleleni zokubonisa i-insulin nezinye izici zokukhula, ngaleyo ndlela isize ukuthuthukisa ukukhula kwemisipha.

I-Immunomodulatory kanye ne-anti-inflammatory: I-Asanalide inezakhiwo zokuzivikela kanye ne-anti-inflammatory ezingathuthukisa ukusebenza komzimba, ukucindezela izimpendulo zokuvuvukala, nokunciphisa ingozi yezifo ezivuthayo ezingapheli.

I-Antioxidant kanye Ne-Antiaging: I-Witanalide inezinto ezibalulekile ze-antioxidant ezingalwa nomonakalo wama-radical wamahhala futhi zivikele amaseli emonakalweni we-oxidative stress.

Ngaphezu kwalokho, i-ananalides kukholakala ukuthi ikhuthaza ukuvuselelwa kabusha nokulungiswa kwamaseli, okungasiza ekunqandeni ukuguga futhi kuthuthukise impilo yesikhumba. Impilo yokuzala kanye nokulingana kwamahomoni: Olunye ucwaningo luphakamisa ukuthi ama-analides angaba nomthelela omuhle empilweni yokuzala kanye nokulingana kwamahomoni kokubili kwabesilisa nabesifazane.

Kukholakala ukuthi ikhuthaza ukuhlanganiswa nokulinganisela kwamahomoni ocansi, ngaleyo ndlela ibe nomthelela omuhle emsebenzini wocansi kanye nempilo yokuzala. Fingqa: I-Witanolides ithathwa njengengxube yezitshalo yemvelo enamandla okusebenza.

Ukusetshenziswa kwayo ekudleni kwezemidlalo, i-immunomodulation, anti-inflammatory, antioxidant, anti-aging kanye nempilo yokuzala iyathandeka. Ngocwaningo olwengeziwe kanye nentuthuko mayelana nama-analides, kulindeleke ukuthi kufakwe emakethe eminye imikhiqizo esezingeni eliphezulu futhi emisha ene-analides, ilethe amathuba engeziwe kanye nezinzuzo empilweni nasenhlalakahleni yabantu.