I-aminobutyric acid

I-aminobutyric acid(I-Gamma-Aminobutyric Acid, efushanisiwe njenge-GABA) iyi-amino acid ebaluleke kakhulu ekhona ebuchosheni bomuntu nezinye izinto eziphilayo.Idlala indima ye-inhibitory transmitter ohlelweni lwezinzwa, olungasiza ekulawuleni umsebenzi wesimiso sezinzwa esimaphakathi nokugcina ibhalansi yezimpawu zemizwa.Ucwaningo lweminyaka yamuva lubonise ukuthi i-GABA inezinzuzo ezihlukahlukene zempilo yomuntu, kusukela ekuthuthukiseni ikhwalithi yokulala kuya ekudambiseni ukukhathazeka, ukucindezeleka, njll, okubonisa amandla ahlaba umxhwele.Ucwaningo lwakamuva lubonise ukuthi i-GABA inomthelela omkhulu ekuthuthukiseni izinga lokulala.Ukulala kubhekwa njengenqubo yomzimba yokulungisa nokuvuselela, futhi izinga lokulala eliphansi lingaba nomthelela omubi empilweni yabantu.I-GABA ingalawula ukuqhutshwa kwezinzwa nokuvinjelwa ngokuthinta ama-GABA receptors ebuchosheni, futhi ikhuthaze ukuphumula komzimba nokulala.Ucwaningo luye lwathola ukuthi ukusebenzisa izithasiselo ze-GABA kunganciphisa kakhulu isikhathi sokulala, ukuthuthukisa ikhwalithi nobude besikhathi sokulala, futhi kunciphise inani lokuvuka ebusuku, ngaleyo ndlela kusize abantu bathole ukuphumula nokululama okungcono.Ngaphezu kwezinzuzo zayo ekuthuthukiseni ukulala, i-GABA iphinde yaboniswa ukusiza ukukhulula ukukhathazeka nokucindezeleka.Impilo enengcindezi ephezulu kanye nendawo yokusebenza esheshayo yomphakathi wanamuhla yenza abantu abaningi babhekane namazinga ahlukene okukhathazeka nokucindezeleka.I-GABA inganciphisa ukukhululwa kwe-neurotransmitter glutamate ngokusebenzisana nama-GABA receptors, ngaleyo ndlela yehlise ukujabula kwesimiso sezinzwa futhi ikhulule ukukhathazeka nokungezwani.Ucwaningo luye lwabonisa ukuthi ukwesekwa kwe-GABA yesikhathi eside kunganciphisa kakhulu imizwa yokukhathazeka nokucindezeleka, futhi kuthuthukise impilo yengqondo kanye nokuphila kahle.Ukwengeza, i-GABA ingasiza ukusekela ukusebenza kwengqondo kanye nempilo yobuchopho.Ubuchopho bungesinye sezitho ezibaluleke kakhulu emzimbeni womuntu futhi bubalulekile ekusebenzeni kahle kokuqonda nokucabanga.Ucwaningo luye lwathola ukuthi i-GABA ingakhuthaza umsebenzi we-GABA receptors, ithinte ukudluliselwa kwesignali nomsebenzi we-neuron ebuchosheni, ngaleyo ndlela ithuthukise ukunaka, ikhono lokufunda kanye nenkumbulo.Okutholakele kuvula amathuba amasha okubhekana nokuguga nokuvimbela izifo ezifana ne-Alzheimer's.Njengoba ucwaningo lwe-GABA luqhubeka nokujula, imikhiqizo eminingi yezempilo nokudla kwezempilo iqala ukwengeza i-GABA njengesithako esibalulekile.Kusukela kuzithasiselo zomlomo kuya eziphuzweni, ukudla, njll., uhla lokusetshenziswa kwe-GABA lukhula njalo.Kodwa-ke, abathengi badinga ukunaka ikhwalithi nomthombo wemikhiqizo lapho bethenga imikhiqizo ye-GABA, futhi bakhethe izinhlobo nemikhiqizo ethembekile.Ukusetshenziswa okubanzi kwe-GABA kuhlobene eduze nemiphumela yayo emihle kakhulu yezempilo.Ngeke nje inikeze ikhwalithi yokulala ethuthukisiwe, ikhulule ukukhathazeka nokucindezeleka, kodwa ingathuthukisa ukusebenza kobuchopho futhi ithuthukise impilo yengqondo.Ngokuzayo, ngocwaningo olujulile lwe-GABA kanye nokunaka okuqhubekayo kwabantu kwezempilo, kukholakala ukuthi i-GABA izodlala izindima zezempilo ezibaluleke kakhulu futhi isize abantu bathole izinga elingcono lempilo.